More than 100 compounds already isolated from the aegle marmelos correa but umbelliferone. Interaction of active compounds from aegle marmelos. Biological activities and volatile constituents of aegle. Pdf a new natural product oxazoline derivative named aeglemarmelosine 1 along with eight known compounds 29 were isolated from roots and twigs of. Introduction diabetes mellitus is the one of the challenging health problem in twentyfirst century that is occurring throughout the world today. The bael tree is one of the most useful medicinal plants of india. All structures were characterized by extensive 1d and 2d nmr spectroscopic methods. Chemical tests were performed for phytochemical screening and dpph is used for antioxidant assay. Studies on the antidiarrhoeal activity of aegle marmelos. Correa fruit, journal of food science and technology on deepdyve, the largest online rental service for scholarly research with thousands of academic publications available at your fingertips. However, despite its traditional usage as an antidiarrhoeal there is limited information regarding its mode of action in infectious forms of diarrhoea. Proximate and phytochemical screening of the fruit and leaves. College of pharmacy 1, shree ganpati institute of technology, nh24, opp.
Interaction of active compounds from aegle marmelos correa. And more over the aegle marmelos possess the bioactive chemicals in the leaves which is available throughout the year and also easy source for collection. The fruit is eaten by humans when ripe, used as feed to animals and for ethnomedical treatment of diseases 9. Biological activities and volatile constituents of aegle marmelos. And its polyherbal marketed formulations nitu singh and shiva kumar department of pharmacognosy, nims institute of pharmacy, nims university, jaipur, rajasthan, india.
Dgalactopyranoside isolated first time in this plant. Antidiabetic activity medicinal plant aegle marmelos. The gcms analysis revealed the presence of many bioactive compounds such as flavonoids, alcohols, aldehydes, aromatic compounds, fatty acid methyl esters, terpenoids, phenolics, and. Lokapure3 1department of home science, agricultural extension unit, koppal, karnataka, india 2department of home science, krishi vigyan kendra, bagalkot, karnataka, india. Nutritional and antioxidant potential of aegle marmelos. Marmelosin based standardization of ayurvedic formulations. International research journal of pharmaceutical and. The therapeutic value of aegle marmelos correa rutaceae, commonly known as bael, has been recognized as a component of traditional medication for the treatment of various human ailments. Tlc and hplc fingerprint development of aegle marmelos corr. Of 14 alkaloids of haplophyllum screened for cytotoxic activity the furoquinoline, haplamine, was the most active o. Aegle marmelos fruit pulp reported for the availability of steroids, terpenoids, flavonoids, phenolic. Medicinal values of bael aegle marmelos l docdeveloppement. Evaluation of antioxidant potential and phytochemical.
Phytochemical analysis of chloroform leaf extract of aegle marmelos s. The mic of aqueous and methanol extract of aegle marmelos ranged from 10 mgml to 40 mgml whereas in aqueous. The antimicrobial property of olive leaf water extract is due to the presence of alkaloids, tannins, saponins and flavonoids. Rutaceae, also known as bael tree, is an herbal traditional remedy. Review article phytopharmacological properties of aegle.
The total phenol contents in aqueous, acetone and methanol extract of aegle marmelos fruit have been estimated. High performance liquid chromatographic determination of. Phytochemical evaluation, antimicrobial activity, and. Compounds 5 and 6 were also detected from the twigs. Aegle marmelos, a plant indigenous to india has been used by the inhabitants of the indian subcontinent for over 5000 years. Introduction herbalism is a traditional medicinal or folk medicine practice based on the use of plants and plant extracts. Proximate and phytochemical screening of the fruit and. In this study, a highperformance liquid chromatography hplc method for the simultaneous quantification of. Science college, affiliated to university of mumbai, linking road, bandraw, mumbai, india400050 abstract herbal medicine constitutes major component in earlier and traditional medical systems evolved in india especially in ayurveda. It has a great mythological significance for hindus.
Biological activities of crude extracts and chemical constituents of bael, aegle marmelos l. All parts of aegle marmelos are medicinally useful. Phytochemical analysis on leaf extract of aegle marmelos correa. Different part of the plant aegle marmelos having the very long history to cure the diabetes but the lack of single bioactive compound was still unknown. Read high performance liquid chromatographic determination of marmelosin and psoralen in bael aegle marmelos l. Corr a medicinally important plant johnson m department of plant biology and plant biotechnology, st. In ayurveda, bael is utilized for its ability to treat an assortment of diseases, including diarrhea, dysentery, and. The chemical investigation of the leaves of this plant has revealed the presence of a number of alkaloids 27 and coumarins. Anuradha verma 1, babita kumar 1, perwaiz alam 1, vijendra singh 2 and shiv kumar gupta 1. The leaves of bael aegle marmelos are used extensively in the feeding of ruminants as well as for treating different ailments in herbal medicine. Phytochemical analysis on leaf extract of aegle marmelos correa sonu singh, neeta singh abstract aegle marmelos is a subtropical plant which can grow up to an altitude of 1200 m from the sea level. Chemical composition aegle marmelos having variety of classes of compound like alkaloids, cardiac glycoside. The tree is used in several cooking preparations in india.
Effects of aqueous extract of aegle marmelos root on chronic. All of the couplings interaction between protons were confirmed by cosy spectrum, such as the crosspeaks which were due to the interaction between h7 and h8 and between appropriate aromatic protons table 1. The aim of present study was to investigate the phytoconstituents present within the aqueous and methanol extract of aegle marmelos seeds and to estimate the total phenolic contents. Chemical composition, antimicrobial and antifungal activities of essential oils of the leaves of aegle marmelos l. Development of value added products from bael fruit aegle marmelos k. Phytochemical composition of aegle marmelos different organic extracts of the leaves of a. Phytochemical analysis and antioxidant property of aegle. Biological activities and volatile constituents of aegle marmelos l. Physico chemical analysis of bael aegle marmelos fruit pulp. Nadhiya and vadivazhagi antioxidant and phytochemical properties of combination international research journal of pharmaceutical and biosciences irjpbs 2015. Marmelosin is one of the major phytoconstituent in aegle marmelos fruits and reported to possess antihyperlipidaemic, hepatoprotective and antidiarrhoeal activities. Biological activities of crude extracts and chemical. This is a clinical verification of the drug aegle marmelos. Aegle marmelos, rutaceae, phytochemical constituents, pharmacological activity.
A number of chemical constituents and various therapeutic effects of a. Its medicinal properties have been described in the ancient medical treatise jn sanskrit, charaka samhita. Effects of aqueous extract of aegle marmelos root on. Medicinal properties of aegle marmelos were well explained in ayurveda, indian traditional medicine.
Broadly, aegle marmelos leaves contain alkaloids, phenylpropanoids. It is present in sri lanka, tamilnadu, thailand, and malesia as a naturalized species. Hence, methanolic extracts of aegle marmelos and ayurvedic formulations were prepared and used for the estimation of marmelosin. Hence, we evaluated the hot aqueous extract decoction of dried unripe fruit pulp of a.
In the present study, an attempt has been made to ferment the a. Research article protective effect of aqueous extract of. Compounds 16 were isolated from the roots whereas compounds 79 were obtained from twigs. The other vernacular names are enlisted in table 1. Phytochemistry and medicinal uses of the bael fruit aegle. Clinical verification validates proving symptoms, filters false indications and serves more authenticated symptoms. Aegle marmelos commonly known as bael is a plant indigenous to india. Healing power and curative properties of aegle marmelos.
The total alcoholic, total aqueous, whole aqueous and methanolic extracts isolated from the. Aegle marmelos or bael is a middle sized slender aromatic armed tree native to india and pakistan. Aegle marmelos benefits and medicinal uses of aegle. Aegle marmelos linn correa commonly known as bael or bel belonging to the family rutaceae, is a moderate sized, slender and aromatic tree. Correa has been widely used in indigenous systems of indian medicine due to its various medicinal properties. Development of value added products from bael fruit aegle. Bael is a slow growing, tough subtropical tree and is the only plant belonging to the. Bael leaves contained aegeline, lupeol, rutin, marmesinine. Bhaskara rao molecular and microbiology research laboratory, environmental biotechnology division, school of bio science and technology, vit university, vellore, tamil nadu, india. Tlc and hplc fingerprint development of aegle marmelos. Unripe fruits show antiviral activity and prove to be a potent hypoglycemic agent. Edible uses fruit eaten raw or made into marmalades, jams, jellies, drinks etc287. Physico chemical analysis of bael aegle marmelos fruit.
The chemicals and reagents used for the purpose of preliminary phytochemical test were freshly prepared. Chemical constituents present in differ ent parts of aegle marmelos. Rutaceae, a native indian plant, has been used as a food and an important ingredient of ayurvedic formulations for centuries. Phytochemical screening and estimation of total phenolic. However, it is not a legal authority for statutory or regulatory purposes.
Flavnoids, alkaloids and terpenoids phytochemicals were found in aegle marmelos extract. Introduction herbalism is a traditional medicinal or folk medicine. Pdf biological activities of crude extracts and chemical. It grows well in the dry forests of hilly and plain areas. Aegle marmelos fruit, leaf and bark, are traditionally used for treatment of diabetes, liver toxicity, fungal infection, microbial infection, inflammation and pyrexia. Serr is one of the important plant with several medicinal and nutraceutical properties. Oct 20, 20 more than 100 compounds already isolated from the aegle marmelos correa but umbelliferone. Aegle marmelos, alloxan, antidiabetic, hyperglycemia. Chemical composition, antimicrobial and antifungal. This plant is having great potential to cure the disease like diabetes, cholesterol, peptic ulcer, inflammation, diarrhoea, and dysentery, anticancer, cardio protective, anti bacterial. The present study is based on the pharmacological activity of aegle marmelos, commonly known as a bael in india. In ayurveda, bael is utilized for its ability to treat an assortment of diseases, including diarrhea, dysentery, and dyspeptic symptoms.
The bole, which is usually fluted at base, can be 50cm in diameter. Phytochemical analysis on leaf extract of aegle marmelos. Chemical composition, antimicrobial and antifungal activities. General information bael tree is a slowgrowing deciduous shrub or tree that can reach an eventual height of 10 15 metres.
Aegle marmelos linn correa, commonly known as bael or bel, belonging to the family rutaceae, is a moderate sized, slender and aromatic tree. The present research work is aimed to summarize the ethnobotanical and pharmacological aspects of d. Aegle marmelos correa rutaceae is a prominent species in the subhimalayan region, also found in central and south india, and has been widely used as remedy for diarrhea and dysentery. The leaves, bark, roots, fruits and seeds are used extensively in the indian traditional system of medicine the ayurveda and in various folk medicine to treat myriad ailments. This study was designed to elucidate the toxicity of the widely used plant aegle marmelos in rats. Aegle marmelos, oxazoline, coumarins, alkaloids and rutaceae. Utilization of bael in daytoday life has great nutritional, environmental as well as commercial importance. International research journal of pharmaceutical and applied. The plant, though, being highly explored, still lacks sufficient evidences for the best variety possessing the highest degree of medicinal values. The chemical compositiondeter, mined by gcms, revealed 82 compounds, with 81.
The current study was initiated to explore the composition of the essential oil leaves in of. While every effort has been made to provide the most reliable and uptodate information available, ultimate legal requirements with respect to species are contained in. Simultaneous quantification of furanocoumarins from aegle. A number of chemical constituents and various therapeutic effects of leaves of aegle marmelos have been reported by different workers. Aegle marmelos linn correa, commonly known as bael or bel, belonging to the family rutaceae, is a moderatesized, slender and aromatic tree.
A new natural product oxazoline derivative named aeglemarmelosine 1 along with eight known compounds 29 were isolated from roots and twigs of aegle marmelos. Various phytoconstituents have been isolated from the various parts of. A number of biologically active compounds isolated from various parts of a. Various chemical constituents like alkaloids, coumarins and steroids have been isolated and identified from different parts of tree such as leaves, fruits, wood, root and bark. Aegle marmelos international research journal of pharmacy. The amount of total phenols, were analyzed using a. Itis taxonomy is based on the latest scientific consensus available, and is provided as a general reference source for interested parties. Tremendous pharmacological values of aegle marmelos. A number of chemical constituents and various therapeutic effects of leaves of a. Pdf chemical constituents from aegle marmelos researchgate. Chemical constituents from aegle marmelos article pdf available in journal of the brazilian chemical society 221. In colloquial terms they are known as bengal quince, indian quince, holy fruit, golden apple in english, and bael or bilva in hindi chemexcil, 1992, sharma et al.
1216 1299 1044 1214 1404 249 1158 284 646 58 257 1283 232 347 313 953 402 916 348 1394 1153 1025 1044 723 1209 143 166 464 324 520